Side effects of sedating antihistamines
Also, diphenhydramine and doxylamine — sedating antihistamines often found in over-the-counter sleep aids — aren't recommended for people who have certain conditions, such as closed-angle glaucoma, asthma, chronic obstructive pulmonary disease or severe liver disease.
Diphenhydramine and doxylamine have anticholinergic properties that make them poor choices for older adults.
Start with lifestyle changes instead: If you continue to have trouble falling or staying asleep, consult your doctor.
In addition to lifestyle changes, your doctor might recommend ways to make your sleeping environment more conducive to sleep or suggest behavior therapy to help you learn new sleep habits.
Antihistamines induce drowsiness by working against histamine, a chemical produced by the central nervous system.
In fact, most over-the-counter sleep aids contain antihistamines.
If you're struggling with chronic insomnia, don't rely on antihistamines or other over-the-counter sleep aids for a good night's sleep.
Pharmacological and clinical studies indicate that hydroxyzine in therapeutic dosage does not increase gastric secretion or acidity and in most cases has mild antisecretory activity.
Hydroxyzine is rapidly absorbed from the gastrointestinal tract and Hydroxyzine Pamoate's clinical effects are usually noted within 15 to 30 minutes after oral administration.
In some cases, short-term use of prescription sleep aids might be recommended as well.
Hydroxyzine Pamoate is a light yellow, practically odorless powder practically insoluble in water and methanol and freely soluble in dimethylformamide.